Transgenic Mouse Services

Introduction

Creating a transgenic mouse requires several critical steps:

Designing an effective transgenic expression cassette
Purifying high quality DNA for pronuclear microinjection
Successful pronuclear microinjection and embryo transfer
Genotyping of mouse tail biopsies to identify potential founder mice
Breeding of founders to establish the transgenic line

Summary

Our team creates transgenic mice by pronuclear injection of transgenic expression cassettes prepared by investigators. Our standard strain for injection is (C57BL/6J X SJL/J) F2, but other strains (e.g. C57Bl/6, FVB) are available.

CD Genomics has already updated its technology platforms to mainstream NGS, long-read sequencing, and microarray instruments. We continue to strive to offer the same reliable services to pharmaceutical and biotechnology companies, as well as academia and government agencies, for all your sequencing or array needs. If you are interested, please contact us directly for assistance.