Transgene Het-Hom Genotyping Services

Introduction

Determine the Heterozygous or Homozygous status of randomly inserted transgenes using copy number testing
Monitor the genetic stability of the copy number

Service Features

Select the most appropriate breeders based on genotype e.g. Het vs Hom. Removing the guess work when trying to breed to a specific genotype
Reducing time taken to breed to required genotypes
Reduce the number of animals born and subsequently culled
A tool to monitor copy number variability over time for uncharacterised strains
A tool to investigate unexpected changes in phenotypic characteristics

Sample Submission

Samples submitted should follow the definition of a ‘standard sample’ found in our service agreement
Please collect two samples per animal if you have not used this service before, this will allow us to validate custom test designs
If submitting samples for Het / Hom determination, please ensure the animal has previously been genotyped as Transgene Positive to avoid processing samples that are not carrying the Transgene.
If studying variability in copy number, we recommend submitting samples from an appropriate number of animals across a number of litters.

CD Genomics has already updated its technology platforms to mainstream NGS, long-read sequencing, and microarray instruments. We continue to strive to offer the same reliable services to pharmaceutical and biotechnology companies, as well as academia and government agencies, for all your sequencing or array needs. If you are interested, please contact us directly for assistance.