Single Cell Genomics Service—10× Genomics Chromium

Single-cell genomics is the study of the genome and transcriptome at the single-cell level. With the development of high-throughput sequencing technology, single-cell genomics has also developed rapidly, and various applications of sequencing technology in single-cell genomics are emerging. CD Genomics enables the functional identification and classification of cells at the single-cell level, thus providing useful information for future developments in medicine and biology.

Name of the Instrument/Technicial Service

10× Genomics Chromium

Summary

We provides two 10× Genomics Chromium Controllers with multiple supporting instruments for transcriptomic and epigenomic profiling at single cell resolution. The Chromium device uses microfluidic partitioning to capture single cells or nuclei in GEM (Gel Bead-in-Emulsion), generating molecular and cellular barcoded nucleic acids to construct Illumina sequencing libraries. Each microfluidic chip has eight channels, allowing up to eight samples partitioned in parallel with each containing 500-10,000 cells. Single cell RNA-seq reveals the full complexity of cellular diversity in a sample. With the combination of simultaneous detection of additional analytes, such as cell surface proteins and CRISPR edits, researchers will gain deeper insights into cell types and states. Furthermore, single cell ATAC profiles genome-wide open chromatin fragments for hundreds to tens of thousands of nuclei per chip, deepening our understanding of gene regulatory mechanisms.

CD Genomics offers you 10× Genomics Chromium based single cell genomics services that can solve problems that ordinary genomics cannot. If this is of interest to you, please contact us directly for details.

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