PCR-Free Libraries Services

Introduction

Libraries generated without amplification will reduce library prep biases. Thus, they can improve the sequencing coverage of genomic areas such as GC-rich regions, promoters, and repeat regions, and enhancing the detection of sequence variants. Please note that PCR-free libraries are more difficult to QC and quantify and that the yields tend to be lower for these libraries compared to amplified libraries (10-15%). PCR-free library prep will also require a greater amount of starting material (>5 fold).

CD Genomics has already updated its technology platforms to mainstream NGS, long-read sequencing, and microarray instruments. We continue to strive to offer the same reliable services to pharmaceutical and biotechnology companies, as well as academia and government agencies, for all your sequencing or array needs. If you are interested, please contact us directly for assistance.