Gene Targeting Services

CD Genomics is the pioneer in genomics research. Our experts and technicians are knowledgeable and have years of experience providing Gene Targeting Services.

Name of the Instrument/Technicial Service

Gene Targeting Services

Introduction

We offer several services to accommodate your ES cell mutagenesis/transgenesis requirements. Your gene of interest may have already been mutated or conditionally disrupted via the numerous ES cell gene trapping and gene targeting resources that currently exist.

Our Services

Ploidy analysis: As diploidy is needed for germline transmission success, we offer an optional ploidy analysis.
Cre excision: We can pursue a cre deletion experiment in ES cells.
MEF derivation: We can generate Mouse Embryonic Feeders (MEFs) from your favorite mouse mutant.
ES cell line derivation: We can derive novel ES cell lines from your favorite mutant mouse.
ES cell line expansion: We can receive and expand cell lines coming from other laboratories.
ES cell sub-cloning: We offer ES cell subcloning to enrich for undifferentiated or diploid cells.
Custom projects: We can perform individualized ES cell culture for your specific project. For example, we can assist you with differentiating ES cells into your favorite cell type of interest.
Mycoplasm Testing: We can confirm whether your cell lines have been contaminated with mycoplasm.
Supplies & reagents: We offer ES cell culture tested supplies, reagents and cells including primary CD1, DR4, pPGKneo Mefs or mitomycin inactivated DR4, pPGKneo Mefs. As well LIF, ES cell tested FBS and other supplies can be purchased from us.

CD Genomics offers various solutions, from genome-wide association studies on tens of thousands of samples to single SNP interrogations of several hundred individuals. Our experts and technicians are knowledgeable and have years of experience providing Gene Targeting Services.