CRISPR/Cas9 Gene Editing Services

Introduction

We are now using CRISPR/Cas9 to create targeted mutations directly in embryos or in embryonic stem (ES) cells. We have successfully used this technology to create the following mutations directly in single-cell fertilized embryos:
KO mutations
Single point mutation KI
Simultaneous targeting/functional deletion of two genes
Insertion of epitope tags within first exon to create tagged fusion protein
New mutations in established mutant mouse lines
Conditional KO: simultaneous insertion of LoxP sites of 5’ and 3’ of critical exon(s)

CD Genomics has already updated its technology platforms to mainstream NGS, long-read sequencing, and microarray instruments. We continue to strive to offer the same reliable services to pharmaceutical and biotechnology companies, as well as academia and government agencies, for all your sequencing or array needs. If you are interested, please contact us directly for assistance.